A special military unit fights a powerful, out-of-control supercomputer and hundreds of scientists who have mutated into flesh-eating creatures after a laboratory accident.

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When human forces discover the existence of the Vampire and Lycan clans, a war to eradicate both species commences. The vampire warrioress Selene leads the battle against humankind.

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An origins story centered on the centuries-old feud between the race of aristocratic vampires and their onetime slaves, the Lycans.

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Selene, a beautiful vampire warrior, is entrenched in a war between the vampire and werewolf races. Although she is aligned with the vampires, she falls in love with Michael, a werewolf who longs for the war to end.

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Picking up directly from the previous film, vampire warrior Selena and the half werewolf Michael hunt for clues to reveal the history of their races and the war between them.

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